NORYVA
MOTS-c
Metabolism: a lead that began with an observation in humans.
10 mg
MOTS-c is a peptide whose blueprint does not come from the centre of the cell, but from its small power plants — a rare origin, and the reason it is studied apart. The work starts from an observation made in humans: effort raises the amount in the blood, and that level tracks measures of fat mass, lean mass and blood sugar.
- Metabolism and blood sugar.
- Fat mass and lean mass.
- No published trial that administers it.
What is being looked at?
- Metabolism
- Blood sugar
- Body composition
The essentials
- Format
- 10 mg
- Storage · Batch number · Manufactured · Expiry · Batch purity
- On the batch certificate
- Evidence level
- Mechanistic
- Use
- For research and laboratory use only.
The question you are asking yourself
Has any study actually given it to people?
Not published yet. The first trial administering it is recruiting. What exists today are measurements made on the MOTS-c the body produces itself, during exercise programmes — an association, never the effect of a product. The difference matters, and we keep it written down.
Why this reference?
A peptide that comes from the mitochondria rather than the cell nucleus: that origin alone is a reason to study it separately. What started the research is an observation made in humans — exercise raises the amount of it in the blood, and that level goes together with measurements of fat mass, lean mass and blood sugar. This work observes the MOTS-c the body makes itself; the first human trial that administers it is under way and has not published.
What you should know
Scientific detail
What it is
MOTS-c is a sixteen-amino-acid peptide encoded by mitochondrial DNA rather than by nuclear DNA. That origin is what makes it studied separately.
Why it is studied
Mitochondria-derived peptides are a recent research subject: the question is whether they act as signals between the mitochondrion and the rest of the cell.
Described mechanism
Proposed mechanism: involvement in cellular metabolic pathways. The peptide's physiological role is not established.
What the research has studied
- Mitochondrial function
- Metabolism
- Signals inside the cell
Human data
No clinical trial published to date. The available work is experimental.
Preclinical data
In vitro and animal-model data, mainly metabolic.
What the data does not say
Young research field, results to be confirmed. No marketing authorisation. A molecule's mitochondrial origin says nothing about its safety.
Regulatory status
For laboratory research purposes only. Not for human consumption or therapeutic use.
This reference holds no marketing authorisation as a medicinal product.
Customer reviews
Frequently asked questions
Can I order MOTS-c today?
No. This reference is not offered for sale: its commercial framework is not settled. No purchase button is shown until it is.
Does MOTS-c hold a marketing authorisation?
No. This reference holds no marketing authorisation as a medicinal product and is approved by no authority for human use. A publication or a clinical trial never amounts to approval.
What analyses are available?
The certificate of analysis is supplied with the batch delivered. No batch number or purity figure is published until the real certificate has been entered: we do not display illustrative values.
How is this reference stored?
The storage requirement is not yet on file: the supplier data sheet has not reached us. We would rather say so than assume.
Is it compatible with the NORYVA injector pen?
Compatibility is not confirmed for this reference. Until the manufacturer confirms it, we do not claim it.
What does the available data actually show?
Young research field, results to be confirmed. No marketing authorisation. A molecule's mitochondrial origin says nothing about its safety.
Work out a volume
The vial amount is prefilled from this page. The solvent volume and the amount aimed for are yours to enter: NORYVA proposes neither.